Article

Implications of Parkinson’s disease-associated alterations in the oral and gut microbiome on vitamin B12 biosynthesis and levodopa bioavailability

2022-06-01

Abstract excerpt

<title>Abstract</title> <p>Small intestinal bacteria harboring tyrosine decarboxylase (TDC) activity was shown to reduce levels of the main treatment for Parkinson’s disease (PD), levodopa. However, it remains obscure whether the relative abundance of bacterial-TDC in the oral cavity and/or feces contributes to the decreased levodopa bioavailability and the frequency of dosage regimen of levodopa treatment. Shotg...

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Literature Corpus work: 5f5f5552-a723-5e15-a00d-f30a66080908
DOI: 10.21203/rs.3.rs-1685667/v1

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