Systematic mapping of drug metabolism by the human gut microbiome

Abstract excerpt

<h4>ABSTRACT</h4> The human gut microbiome harbors hundreds of bacterial species with diverse biochemical capabilities, making it one of nature’s highest density, highest diversity bioreactors. Several drugs have been previously shown to be directly metabolized by the gut microbiome, but the extent of this phenomenon has not been systematically explored. Here, we develop a systematic screen for mapping the abilit...

Topics

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• Clostridium difficile and Clostridium perfringens research
• Diet and metabolism studies
• Ginseng Biological Effects and Applications
• Gut microbiota and health
• Liver Disease Diagnosis and Treatment
• Metabolomics and Mass Spectrometry Studies
• Pharmacogenetics and Drug Metabolism
• Probiotics and Fermented Foods

Identifiers and source

Literature Corpus work

44baa476-cd8a-5a30-acf0-f60623c0c2d4

DOI

10.1101/538215