Article

Generating Patient-Derived HCC Cell Lines Suitable for Predictive In-Vitro and In-Vivo Drug Screening by Orthotopic Transplantation

2023-11-30

Abstract excerpt

Hepatocellular carcinoma (HCC) results in high mortality due to ineffective systemic therapy. Human immortalized cell lines are commonly used to study anti-tumour effects in the context of new anti-tumour therapies and tumour biology. As immortalized cell lines have limited biological relevance and heterogeneity compared to primary cells, patient-derived tumour tissues and corresponding immune cells are the gold s...

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Literature Corpus work: 96df0f7f-8be5-55d6-9af2-98f18fa5f6ef
DOI: 10.20944/preprints202311.1972.v1

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