Article

A personalized medicine approach identifies enasidenib as an efficient treatment for IDH2 mutant chondrosarcoma

2023-09-12

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Sarcomas represent an extensive group of malignant diseases affecting mesodermal tissues. Among sarcomas, the clinical management of chondrosarcomas remains a complex challenge, as high-grade tumors do not respond to current therapies. Mutations in the isocitrate dehydrogenase ( IDH ) 1 and 2 genes are among the most common mutations detected in chondrosarcomas and may rep...

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Literature Corpus work: 96dd1491-c4fc-5eba-80f7-1c112315185b
DOI: 10.1101/2023.09.12.557334

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