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A study on the attenuation of ATO cardiotoxicity by SOG though Nrf2/ARE pathway

2021-03-15

Abstract excerpt

Arsenic trioxide (ATO, Trisenox) is an ancient Chinese medicine which have good clinical effects for acute promyelocytic leukemia (APL). However, ATO has serious cardiotoxicity which has restricted its widely applied in clinic. Saposhnikovia divaricata (Trucz.) Schischk was an antidote to ATO in Chinese medical book. Sec-O-Glucosylhamaudol (SOG) is one of its four main active ingredients. So we explore if SOG can...

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Identifiers and source

Literature Corpus work
96cd7324-f063-5973-b78d-5e91b092d01e
DOI
10.21203/rs.3.rs-177594/v1
Open publication

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A study on the attenuation of ATO cardiotoxicity by SOG though Nrf2/ARE pathwayDOI 10.21203/rs.3.rs-177594/v1
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