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Effect of a Dietary Intervention on Weight Loss in Adults with High vs Low Genetic Predisposition to Higher BMI: A Randomized Diet Intervention Trial

2025-10-07

Abstract excerpt

<h4>ABSTRACT</h4> It is unclear whether the effectiveness of weight loss interventions differs based on genetic predisposition to higher body mass index (BMI). Genome-wide polygenic scores (PS) for BMI are the strongest genetic predictors of elevated body weight, but no prospective trials have evaluated weight loss responses based on BMI PS. To assess whether adults with high or low genetic predisposition to high...

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Literature Corpus work
96bf4487-993d-5760-a5f5-ca5dfbc25d8b
DOI
10.1101/2025.10.06.25337395
Open publication

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Effect of a Dietary Intervention on Weight Loss in Adults with High vs Low Genetic Predisposition to Higher BMI: A Randomized Diet Intervention TrialDOI 10.1101/2025.10.06.25337395
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