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Article

Genetic variation in lean body mass, changes of appetite and weight loss in response to diet interventions: The POUNDS Lost trial.

Diabetes, obesity & metabolism - 1 Dec 2020

Li Xiang, Zhou Tao, Ma Hao, Heianza Yoriko, Champagne Catherine M, Williamson Donald A, Bray George A, Sacks Frank M, Qi Lu

Abstract excerpt

AIM: To investigate whether the genetic risk score (GRS) for lean body mass (LBM) modified the effects of weight-loss diets on changes in appetite and adiposity among overweight and obese individuals. PARTICIPANTS AND METHODS: In the 2-year Preventing Overweight Using Novel Dietary Strategies (POUNDS Lost) trial, we included 692 adults who were randomly assigned to one of four diets varying in macronutrient...

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Identifiers

PMID: 32734691
DOI: 10.1111/dom.14155
PMCID: PMC8197290

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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