Article

WT1-MMP9 regulatory axis and its modulation by TNF-α in early and late onset glaucoma phenotypes

2025-11-07

Abstract excerpt

<title>Abstract</title> <p> Glaucomas comprise a group of heterogeneous optic neuropathies that are linked to extracellular matrix (ECM) dysregulation, aberrant morphogenesis, and inflammatory signaling. Despite overlapping clinical features, the molecular underpinnings in early onset (primary congenital glaucoma [PCG]) and late onset (primary angle closure glaucoma [PACG]) diseases are poorly understood. Herein...

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Literature Corpus work: 96a0c879-3b47-591f-8899-d7823a6d3605
DOI: 10.21203/rs.3.rs-8024902/v1

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