Article

Regulation of BMP genes, EMC production and deposition through TGFβ/Smad Signaling in Human Trabecular Meshwork for progression of glaucoma disease

2022-08-29

Abstract excerpt

Glaucoma is a chronic neurological condition that causes damage to retinal ganglion cells and nerve fibres. The transforming growth factor pathway may have a role in disease progression, but its mechanism and regulation are unknown. We explored the molecular mechanisms behind glaucoma onset and progression utilising a network and systems biology approach. First, we manually curated a glaucoma-related seed network....

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Literature Corpus work: 3ffd0d51-523c-5e30-8dce-ca1f01ae7f0e
DOI: 10.21203/rs.3.rs-1969317/v1

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