Back to search

Article

Modulation of Ferroptosis During Early <i>Mycobacterium tuberculosis</i> Infection Contributes to Beijing Lineage Strain SA161 Virulence

2026-06-04

Abstract excerpt

Although spread of internalized Mtb from the initial infected alveolar macrophages (AMs) is a crucial determinant of infection outcomes, the role of cell death in facilitating this spread, and how it is regulated by Mtb remains poorly understood. Ferroptosis, a lipid peroxidation-mediated form of necrotic cell death, contributes to pathology during later stages of infection. However, the role of ferroptosis in ear...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
968fe5c2-d772-51d6-92ab-77b6af993b3a
DOI
10.64898/2026.05.29.728786
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Modulation of Ferroptosis During Early <i>Mycobacterium tuberculosis</i> Infection Contributes to Beijing Lineage Strain SA161 VirulenceDOI 10.64898/2026.05.29.728786
RNAseq reveals hypervirulence-specific host responses toM. tuberculosisinfectionSemantic proximity
BACH1 promotes tissue necrosis and Mycobacterium tuberculosis susceptibilitySemantic proximity
Lipid Peroxidation and Type I Interferon Coupling Fuels Pathogenic Macrophage Activation Causing Tuberculosis SusceptibilitySemantic proximity
Host‐pathogen dialogues in different cell death modes during Mycobacterium tuberculosis infectionSemantic proximity
Crosstalk of ferroptosis and oxidative stress in infectious diseasesSemantic proximity
Ferroptosis hijacking by Mycobacterium tuberculosisSemantic proximity
A mycobacterial effector promotes ferroptosis-dependent pathogenicity and disseminationSemantic proximity
Cytokine Dynamics and Oxidative Stress in Host Cells Stimulated with Drug-Resistant and Sensitive <i>Mycobacterium tuberculosis</i> IsolatesSemantic proximity
Candidate transmission survival genome of <i>Mycobacterium tuberculosis</i>Semantic proximity
Mycobacterium tuberculosis Induces an Atypical Cell Death Mode to Escape from Infected MacrophagesSemantic proximity
The Role of Ferroptosis and Cuproptosis in Tuberculosis Pathogenesis: Implications for Therapeutic StrategiesSemantic proximity
Tobramycin enhances <i>Mycobacterium abscessus</i> fitness through <i>whiB7</i> inductionSemantic proximity
Select a neighboring publication to make it the new centre.