Article

Knockout IL4I1 affects macrophages to improve poor efficacy of CD19 CAR-T combined with PD-1 inhibitor in relapsed/refractory diffuse large B-cell lymphoma

2024-11-25

Abstract excerpt

<title>Abstract</title> <p>Chimeric antigen receptor (CAR) T-cell therapy plays a critical role in the treatment of B-cell hematologic malignancies. The combination of PD-1 inhibitors and CAR-T has shown encouraging results in treating patients with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL). However, there are still cases where treatment is ineffective. This study aimed to investigate the ro...

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Literature Corpus work: 965042fa-fa2c-5f5b-992b-5417decf1d6b
DOI: 10.21203/rs.3.rs-5149724/v1

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