Back to search

Article

Clinical Impact of Metagenomic Next-Generation Sequencing of Plasma Cell-Free DNA for the Diagnosis of Infectious Diseases: A Multicenter Retrospective Cohort Study

2019-10-08

Abstract excerpt

<h4>Background</h4> Metagenomic next-generation sequencing (mNGS) of plasma cell-free DNA has emerged as an attractive diagnostic modality allowing broad-range pathogen detection, noninvasive sampling, and earlier diagnosis. However, little is known about its real-world clinical impact as used in routine practice. <h4>Methods</h4> We performed a retrospective cohort study of all patients for whom plasma mNGS (Kari...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
95caf35b-9407-5f44-9d01-3f36181e725c
DOI
10.1101/19008755
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Clinical Impact of Metagenomic Next-Generation Sequencing of Plasma Cell-Free DNA for the Diagnosis of Infectious Diseases: A Multicenter Retrospective Cohort StudyDOI 10.1101/19008755
Clinical Impact of Metagenomic Next-Generation Sequencing of Plasma Cell-Free DNA for the Diagnosis of Infectious Diseases: A Multicenter Retrospective Cohort StudySemantic proximity
Plasma Microbial Cell-free DNA Sequencing from Over 15,000 Patients Identified a Broad Spectrum of PathogensSemantic proximity
Comprehensive evaluation of plasma microbial cell-free DNA sequencing for predicting bloodstream and local infections in clinical practice: a multicenter retrospective studySemantic proximity
Comparison of plasma and blood cell samples in metagenomic next-generation sequencing for identification of the causative pathogens of feverSemantic proximity
Clinical Efficacy and Diagnostic Value of Metagenomic Next- Generation Sequencing for Rapid Pathogen Detection in Patients with Suspected Infectious DiseasesSemantic proximity
Clinical Utility and Impact of the Metagenomic Microbial Plasma Cell-Free DNA Next-Generation Sequencing Assay on Treatment Decision: A Single-Center Retrospective StudySemantic proximity
Yield of clinical metagenomics: insights from real-world practice for tissue infectionsSemantic proximity
Assessment of the Clinical Utility of Plasma Metagenomic Next-Generation Sequencing in a Pediatric Hospital PopulationSemantic proximity
The Role of Metagenomics and Next-Generation Sequencing in Infectious Disease DiagnosisSemantic proximity
Sequence-based diagnostics and precision medicine in bacterial and viral infections: from bench to bedsideSemantic proximity
Clinical Impact, Diagnostic Performance, and Prognostic Implications of Plasma Metagenomic Next-Generation Sequencing in Solid Organ Transplant RecipientsSemantic proximity
Clinical and diagnostic values of metagenomic next-generation sequencing for infection in hematology patients: a systematic review and meta-analysisSemantic proximity
Select a neighboring publication to make it the new centre.