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Yield of clinical metagenomics: insights from real-world practice for tissue infections

26 Dec 2024

Abstract excerpt

BACKGROUND: While metagenomic next-generation sequencing (mNGS) has been acknowledged as a valuable diagnostic tool for infections, its clinical validity and impact on patient management when using fresh tissue samples remains uncertain. METHODS: We conducted a retrospective cross-sectional study involving patients who underwent tissue mNGS at a tertiary hospital in China from February 2021 to February 2024,...

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PMID: 39729886
DOI: 10.1016/j.ebiom.2024.105536

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