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The Role of Metagenomics and Next-Generation Sequencing in Infectious Disease Diagnosis

19 Aug 2021

Abstract excerpt

BACKGROUND: Metagenomic next-generation sequencing (mNGS) for pathogen detection is becoming increasingly available as a method to identify pathogens in cases of suspected infection. mNGS analyzes the nucleic acid content of patient samples with high-throughput sequencing technologies to detect and characterize microorganism DNA and/or RNA. This unbiased approach to organism detection enables diagnosis of a broad...

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PMID: 34969106
DOI: 10.1093/clinchem/hvab173

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