Back to search

Article

Clinical Impact, Diagnostic Performance, and Prognostic Implications of Plasma Metagenomic Next-Generation Sequencing in Solid Organ Transplant Recipients

2026-07-06

Abstract excerpt

<h4>Background</h4> Plasma metagenomic next-generation sequencing (mNGS) may detect pathogens in solid organ transplant (SOT) recipients, but optimal patient selection and result interpretation remain uncertain. <h4>Methods</h4> We studied 145 SOT recipients who received Karius plasma mNGS testing between 2017-2025. Retrospective multi-physician adjudication assessed diagnostic accuracy, clinical impact, and out...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
bdac8e23-213a-557b-b531-cfcb8eb94f83
DOI
10.64898/2026.07.02.26357172
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Clinical Impact, Diagnostic Performance, and Prognostic Implications of Plasma Metagenomic Next-Generation Sequencing in Solid Organ Transplant RecipientsDOI 10.64898/2026.07.02.26357172
Clinical Impact of Metagenomic Next-Generation Sequencing of Plasma Cell-Free DNA for the Diagnosis of Infectious Diseases: A Multicenter Retrospective Cohort StudySemantic proximity
Clinical Impact of Metagenomic Next-Generation Sequencing of Plasma Cell-Free DNA for the Diagnosis of Infectious Diseases: A Multicenter Retrospective Cohort StudySemantic proximity
Clinical Utility and Impact of the Metagenomic Microbial Plasma Cell-Free DNA Next-Generation Sequencing Assay on Treatment Decision: A Single-Center Retrospective StudySemantic proximity
Yield of clinical metagenomics: insights from real-world practice for tissue infectionsSemantic proximity
Metagenomic versus targeted next-generation sequencing for detection of microorganisms in bronchoalveolar lavage fluid among renal transplantation recipientsSemantic proximity
The Clinical Significance of Metagenomic Next-Generation Sequencing in Non-Immunocompromised Patients Undergoing Veno-Venous Extracorporeal Membrane for Severe Pneumonia: A single-center, retrospective studySemantic proximity
Comparing the diagnostic value of targeted with metagenomic next-generation sequencing in immunocompromised patients with lower respiratory tract infectionSemantic proximity
Sequence-based diagnostics and precision medicine in bacterial and viral infections: from bench to bedsideSemantic proximity
Metagenomic Next-Generation Sequencing Reveals the Profile of Fungal Infections in Kidney Transplant Recipients: a retrosective studySemantic proximity
Enhanced Pathogen Detection in Hematology Patients with Respiratory Infections Using Targeted Next-Generation Sequencing (tNGS)Semantic proximity
Plasma Microbial Cell-free DNA Sequencing from Over 15,000 Patients Identified a Broad Spectrum of PathogensSemantic proximity
Clinical and diagnostic values of metagenomic next-generation sequencing for infection in hematology patients: a systematic review and meta-analysisSemantic proximity
Select a neighboring publication to make it the new centre.