Article

Endoplasmic Reticulum Stress Promotes Colorectal Cancer Proliferation by Regulating Autophagy via XBP1s

2025-12-30

Abstract excerpt

<title>Abstract</title> <p>Background: X-box binding protein 1 spliced (XBP1s), a key downstream molecule of endoplasmic reticulum stress (ERS), is widely involved in processes such as proliferation, invasion, and apoptosis in cancer. However, the role and underlying mechanism of XBP1s in colorectal cancer (CRC) remain poorly understood. We hypothesize that XBP1s plays a critical role in promoting CRC proliferati...

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Literature Corpus work: 95c9e621-0a8d-588b-9ea7-37bf5c7ddbfb
DOI: 10.21203/rs.3.rs-7981202/v1

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