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BRIX1 Promotes Ribosome Synthesis and Enhances Glycolysis by Selected Translation of GLUT1 in Colorectal Cancer

2021-08-03

Abstract excerpt

<h4>Background: </h4> Ribosome biogenesis protein BRX1 homolog (BRIX1) is a vital member for synthesizing 60S subunit of ribosome. However, the role and mechanism of BRIX1 in colorectal cancer (CRC) are still unclear. <h4>Methods: </h4>: KEGG pathway analysis and Gene Ontology (GO) analysis were used for bioinformatics analysis. Ribosome RNAs (rRNAs) levels were detected in CRC tissues and cells. Nascent RNA synth...

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Literature Corpus work
d89d14d2-bfd0-54c5-8d5f-f4959dd01ddd
DOI
10.21203/rs.3.rs-713733/v1
Open publication

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