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Peripheral blood exosomes pass blood-brain-barrier and induce glial cell activation

2018-11-29

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Exosomes are involved in intracellular communication and contain proteins, mRNAs, miRNAs, and signaling molecules. Exosomes were shown to act as neuroinflammatory mediators involved in neurodegenerative diseases including Alzheimer’s disease (AD), Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS). Brain aging has been associated to increased neuroinflammation. In...

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Literature Corpus work
95c9c96b-23b3-5cba-af40-7b7c4397e13a
DOI
10.1101/471409
Open publication

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