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Article

Distinct repertoires of microRNAs present in mouse astrocytes compared to astrocyte-secreted exosomes

2 Feb 2017

Abstract excerpt

BACKGROUND: Astrocytes are the most abundant cell type in the central nervous system (CNS) and secrete various factors that regulate neuron development, function and connectivity. microRNAs (miRNAs) are small regulatory RNAs involved in posttranslational gene regulation. Recent findings showed that miRNAs are exchanged between cells via nanovesicles called exosomes. In this study, we sought to define which miRNAs...

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PMID: 28152040
DOI: 10.1371/journal.pone.0171418

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