Back to search

Article

Transcriptomic Modulation by Exosomes Derived from Human Adipose Stem Cells in Neuronal Cells: Insights from mRNA Sequencing Analysis

2025-11-03

Abstract excerpt

<title>Abstract</title> <p>Brain aging, which influences neurological function across cellular and molecular domains, is a critical concern in the elderly population. Therapeutic strategies for mitigating age-related neurodegeneration should target molecular pathways that are primarily involved in neuroinflammation. Exosomes derived from human adipose tissue mesenchymal stem cells (hASCs) have demonstrated anti-i...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
ae8a0896-ebb1-5d0b-8852-963fd4518d2c
DOI
10.21203/rs.3.rs-7778530/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Transcriptomic Modulation by Exosomes Derived from Human Adipose Stem Cells in Neuronal Cells: Insights from mRNA Sequencing AnalysisDOI 10.21203/rs.3.rs-7778530/v1
Advances in mesenchymal stem cell and exosome-based therapies for aging and age-related diseasesSemantic proximity
Mesenchymal Stem Cell-Derived Exosomes as a Neuroregeneration Treatment for Alzheimer's DiseaseSemantic proximity
Heat shock-induced exosomes derived from neural stem cells confer marked neuroprotection against oxidative stress and amyloid-β caused neurotoxicitySemantic proximity
Application of Multiomics Approach to Investigate the Therapeutic Potentials of Stem Cell-derived Extracellular Vesicle Subpopulations for Alzheimer’s DiseaseSemantic proximity
Serum Exosomes from a Uniquely Defined Early-Adult Donor Cohort Reprogram Endothelial Transcriptomes Linked to Alzheimer’s PathogenesisSemantic proximity
Comparative effects of hypoxia and serum deprivation on the morphological, structural, chemical, biological and functional characteristics of exosomes from adipose-derived mesenchymal stem cellsSemantic proximity
Unveiling the role of miRNAs from MSC-EVs in neuroinflammation and behavioral impairments induced by chronic alcohol consumptionSemantic proximity
The exosome of adipose-derived stem cells reduces β-amyloid pathology and apoptosis of neuronal cells derived from the transgenic mouse model of Alzheimer's disease.Semantic proximity
IPSC-Derived Neuronal Cultures Carrying the Alzheimer's Disease Associated TREM2 R47H Variant Enables the Construction of an Aβ-Induced Gene Regulatory Network.Semantic proximity
Expression of Exosome Biogenesis Genes is Pervasively Altered by Aging in the Mouse and in the Human Brain During Alzheimer’s DiseaseSemantic proximity
Human Adipose Derived Stem Cell Exosomes Enhance the Neural Differentiation of PC12 CellsSemantic proximity
Enhanced Mitochondrial Function and Delivery from Adipose-Derived Stem Cell Spheres via the EZH2-H3K27me3-PPARγ Pathway for Advanced TherapySemantic proximity
Select a neighboring publication to make it the new centre.