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The gut bacterial natural product colibactin triggers induction of latent viruses in diverse bacteria

2021-06-01

Abstract excerpt

Colibactin is a chemically unstable small molecule genotoxin produced by multiple different bacteria, including members of the human gut microbiome. While the biological activity of colibactin has been extensively investigated in mammalian systems, little is known about its effects on other microorganisms. Here, we discover that colibactin targets bacteria carrying prophages, inducing lytic development via the bac...

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Literature Corpus work
67df0ac3-6c12-5037-b27e-3c81d3338d1e
DOI
10.21203/rs.3.rs-574343/v1
Open publication

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The gut bacterial natural product colibactin triggers induction of latent viruses in diverse bacteriaDOI 10.21203/rs.3.rs-574343/v1
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