Article

A personalized network framework reveals predictive axis of anti-TNF response across diseases

2021-06-18

Abstract excerpt

Personalized treatment of complex diseases has been mostly predicated on biomarker identification of one drug-disease combination at a time. Here, we used a novel computational approach termed Disruption Networks to generate a new data type, contextualized by cell-centered individual-level networks, that captures biology otherwise overlooked when performing standard statistics. The new data-type extends beyond the...

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Literature Corpus work: 95a4bae0-9197-5dd4-a754-8d2a15853c92
DOI: 10.1101/2021.06.16.448558

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