Article

PathExt: a general framework for path-based mining of omics-integrated biological networks

2020-01-21

Abstract excerpt

<h4>Motivation</h4> Large scale transcriptomic data are routinely used to prioritize genes underlying specific phenotypes. Current approaches largely focus on differentially expressed genes (DEGs), despite the recognition that phenotypes emerge via a network of interactions between genes and proteins, many of which may not be differentially expressed. Furthermore, many practical applications lack sufficient sampl...

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Literature Corpus work: 5fde06fc-e027-5f95-b79f-1fec51a6a814
DOI: 10.1101/2020.01.21.913418

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