Article

Characterization of Critical Determinants of ACE2-RBD Interaction

2021-01-29

Abstract excerpt

Despite sequence similarity to SARS-CoV-1, SARS-CoV-2 has demonstrated greater widespread virulence and unique challenges to researchers aiming to study its pathogenicity in humans. The interaction of the viral receptor binding domain (RBD) with its main host cell receptor, angiotensin-converting enzyme 2 (ACE2), has emerged as a critical focal point for the development of anti-viral therapeutics and vaccines. Uti...

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Literature Corpus work: 958a065c-a01b-5fc9-9d5e-bda51b39e62b
DOI: 10.1101/2021.01.29.428773

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