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Article

A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent in vitro

2020-09-18

Abstract excerpt

Effective intervention strategies are urgently needed to control the COVID-19 pandemic. Human angiotensin-converting enzyme 2 (ACE2) is a carboxypeptidase that forms a dimer and serves as the cellular receptor for SARS-CoV-2. It is also a key negative regulator of the renin-angiotensin system (RAS), conserved in mammals, which modulates vascular functions. We report here the properties of a trimeric ACE2 variant,...

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Identifiers and source

Literature Corpus work
681135dc-6a7a-54ef-9161-8a8740e380bb
DOI
10.1101/2020.09.18.301952
Open publication

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A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent in vitroDOI 10.1101/2020.09.18.301952
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