Article

Skin Mast Cells in Marfan Syndrome: Specific Emphasis on Connective Tissue Remodeling

2023-09-06

Abstract excerpt

<title>Abstract</title> <p>Marfan syndrome (MFS) is a hereditary condition accompanied by disorders in the structural and regulatory properties of the connective tissue, including elastic fibers, due to a mutation in the FBN1 gene and the synthesis of abnormal fibrillin 1 glycoprotein. Despite the high potential of mast cells (MCs) to remodel the extracellular matrix (ECM), their pathogenetic significance in MFS...

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Literature Corpus work: 95329646-8fbe-5114-9bb5-a3bd884c24f9
DOI: 10.21203/rs.3.rs-3307006/v1

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