Article

Characterization of sleep in a mouse model of CLN3 disease revealed sex-specific sleep disturbances

2024-05-26

Abstract excerpt

The neuronal ceroid lipofuscinoses (NCLs) are a group of recessively inherited neurodegenerative diseases characterized by lysosomal storage of fluorescent materials. CLN3 disease, or juvenile Batten disease, is the most common NCL that is caused by mutations in the Ceroid Lipofuscinosis, Neuronal 3 ( CLN3 ) gene. Sleep disturbances are among the most common symptoms associated with CLN3 disease, yet this is und...

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Literature Corpus work: 95305243-2ec1-5afb-8306-eadd3d708854
DOI: 10.1101/2024.05.24.595712

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