Article

Profiles of the composite biomarker specific for β-amyloid accumulation in the brain relevant to age and sex

2023-01-13

Abstract excerpt

Accumulation of β-amyloid (Aβ) in the brain occurs in the early phase of Alzheimer’s disease (AD), without symptoms of cognitive decline. Therefore, early detection of the accumulation phase is essential to prevent or delay AD. In this study, we investigated the effects of age, sex, apoprotein-E (ApoE) genotype and cognitive dysfunction on the ratio of Aβ 1-42 , Aβ 1-40 , and amyloid β precursor protein (APP) 669-...

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Literature Corpus work: 952cdbf1-8d28-5a05-901b-b81dfb65696b
DOI: 10.1101/2023.01.13.23284514

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