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Current application of neurochemical biomarkers in the prediction and differential diagnosis of Alzheimer's disease and other neurodegenerative dementias.

European archives of psychiatry and clinical neuroscience - 1 Nov 2012

Genius J, Klafki H, Benninghoff J, Esselmann H, Wiltfang J

Abstract excerpt

In light of the dramatically increasing prevalence of Alzheimer's disease (AD) to be expected in the future, the development of novel therapeutics, improved differential and early diagnostics, and means for the identification of individuals at risk are urgently needed. At present, instruments for a reliable differential diagnosis in clinical dementia, mild cognitive impairment, or prodromal stages have direct...

Topics

Alzheimer Disease
Amyloid beta-Peptides
Apolipoproteins E
Biomarkers
Dementia
Diagnosis, Differential
Genetic Predisposition to Disease
Humans
Neurodegenerative Diseases
Neuroimaging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Peptide Fragments

Predictive Value of Tests

tau Proteins

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Identifiers

PMID: 22986448
DOI: 10.1007/s00406-012-0362-3

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