Article

Acute Mechanical Stress in Primary Porcine RPE Cells Induces Angiogenic Factor Expression and in vitro Angiogenesis

2020-03-20

Abstract excerpt

<title>Abstract</title> <p>Background Choroidal neovascularization (CNV) is a major cause of blindness in patients with age-related macular degeneration. CNV is characterized by new blood vessel growth and subretinal fluid accumulation, which results in mechanical pressure on retinal pigment epithelial (RPE) cells. The overexpression of RPE-derived angiogenic factors plays an important role in inducing CNV. In th...

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Literature Corpus work: 9500777d-6153-585f-a953-28aa6ddfe048
DOI: 10.21203/rs.2.20909/v2

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