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Development of a Collagen-Coated Microfluidic Device to Evaluate Tubular Structure Formation of RF/6A Cells Under Static and Dynamic Flow Conditions

2026-02-05

Abstract excerpt

<title>Abstract</title> <p>This study presents the development of a collagen-coated microfluidic device to model retinal angiogenesis, with a focus on the choroid layer of the outer blood-retina barrier (oBRB). A PDMS-glass microchannel (2 cm × 2 mm × 85 μm) was fabricated and simulated using COMSOL Multiphysics to evaluate shear stress levels under flow rates of 15–45 µL/min. The device generated physiological w...

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Literature Corpus work
7b9b21ff-c213-591e-bbdf-0440d255ce89
DOI
10.21203/rs.3.rs-8645236/v1
Open publication

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Development of a Collagen-Coated Microfluidic Device to Evaluate Tubular Structure Formation of RF/6A Cells Under Static and Dynamic Flow ConditionsDOI 10.21203/rs.3.rs-8645236/v1
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