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Article

Expression of mRNAs, miRNAs, and lncRNAs in Human Trabecular Meshwork Cells Upon Mechanical Stretch

11 May 2020

Abstract excerpt

Purpose: Intraocular pressure (IOP), the primary risk factor for primary open-angle glaucoma, is determined by resistance to aqueous outflow through the trabecular meshwork (TM). IOP homeostasis relies on TM responses to mechanical stretch. To model the effects of elevated IOP on the TM, this study sought to identify coding and non-coding RNAs differentially expressed in response to mechanical stretch. Methods:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32392310
DOI: 10.1167/iovs.61.5.2

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