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Article

Genetic basis of alpha-1,3 galactose epitopes in animal reservoir of coronaviruses

2024-02-06

Abstract excerpt

<title>Abstract</title> <p>The αGal epitope, Galα1-3Galβ1-4GlcNAc-R, is found in all non-primate mammals, lemurs, and New World monkeys but not in Old World monkeys, apes or humans. Humans possess natural anti-αGal antibodies that have been hypothesized to prevent virus spillover through neutralization and complement-mediated inactivation of glycosylated viruses carried by animal hosts. In this study, we cloned t...

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Identifiers and source

Literature Corpus work
94b14ac5-55b6-5a3e-bad1-a8eb203ecd74
DOI
10.21203/rs.3.rs-3927077/v1
Open publication

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Genetic basis of alpha-1,3 galactose epitopes in animal reservoir of coronavirusesDOI 10.21203/rs.3.rs-3927077/v1
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