Article

Xenosialylation: Role in SARS/CoV-2 Post-infectious and Post-vaccination Complications and Common Cause of Hyperimmune/Autoimmune Diseases

2023-12-14

Abstract excerpt

The host glycosylation mechanism synthesizes the carbohydrates of glycoproteins of viral envelopes. Due to the loss of the Cytidine Monophospho-N-Acetylneuraminic Acid Hydroxylase gene by some mammalian species, including humans (negative-CMAH), Neu5Gc is no longer synthesized. Uptake of Neu5Gc by negative-CMAH species, through the intake of food products derived from positive-CMAH mammals, leads to incorporating...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d43ec437-2c41-5a1b-befe-b0650d752029
DOI: 10.20944/preprints202310.0001.v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Xenosialylation: Role in SARS/CoV-2 Post-infectious and Post-vaccination Complications and Common Cause of Hyperimmune/Autoimmune DiseasesDOI 10.20944/preprints202310.0001.v2Read

Afucosylated immunoglobulin G responses are a hallmark of enveloped virus infections and show an exacerbated phenotype in COVID-19Semantic proximity Read

Evolution of sialic acids: Implications in xenotransplant biologySemantic proximity Read

Sialic Acids as Receptors for PathogensSemantic proximity Read

A drug candidate for treating adverse reactions caused by pathogenic antibodies inducible by COVID-19 virus and vaccinesSemantic proximity Read

Antibody glycosylation in inflammation, disease and vaccinationSemantic proximity Read

Host Synthesized Carbohydrate Antigens on Viral Glycoproteins as “Achilles’ Heel” of Viruses Contributing to Anti-Viral Immune ProtectionSemantic proximity Read

Exploitation of glycosylation in enveloped virus pathobiologySemantic proximity Read

Glycans of SARS-CoV-2 Spike Protein in Virus Infection and Antibody ProductionSemantic proximity Read

Evolving roles of glycosylation in the tug-of-war between virus and hostSemantic proximity Read

Human Natural Antibodies to Mammalian Carbohydrate Antigens as Unsung Heroes Protecting against Past, Present, and Future Viral InfectionsSemantic proximity Read

The COVID-19 antibody responses, isotypes and glycosylation: Why SARS-CoV-2 Spike protein complex binding of IgG3 is potentiated in some and immuno-pathologies manifestSemantic proximity Read

Coronaviruses: Is Sialic Acid a Gate to the Eye of Cytokine Storm? From the Entry to the EffectsSemantic proximity Read