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Article

Exosomes containing miRNAs targeting HER2 synthesis and engineered to adhere to HER2 on tumor cells surface exhibit enhanced antitumor activity

2020-10-06

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Exosomes are small, cellular membrane-derived vesicles with a diameter of 50-150 nm. Exosomes are considered ideal drug delivery systems with a wide range of applications in various diseases, including cancer. However, nonspecific delivery of therapeutic agents by exosomes <italic>in vivo</italic> remains challenging. Human epidermal growth factor receptor 2 (HE...

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Literature Corpus work
940c55b9-8fef-57b0-bc69-c9f75ae955e1
DOI
10.21203/rs.3.rs-39552/v3
Open publication

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Exosomes containing miRNAs targeting HER2 synthesis and engineered to adhere to HER2 on tumor cells surface exhibit enhanced antitumor activityDOI 10.21203/rs.3.rs-39552/v3
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