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Targeting Oncofetal Fibronectin and Neuropilin-1 in solid tumors with PL2 peptide

2025-06-10

Abstract excerpt

<title>Abstract</title> <p>To improve the precision and selectivity of anticancer therapies, affinity ligands targeting molecules of the malignancy-associated vascular signature are used. One such target is Fibronectin Extra Domain-B (Fn-EDB), an oncofetal splice variant of a major extracellular matrix protein (Fn), which is upregulated in many solid tumors as part of the angiogenic response. In this study, we co...

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Literature Corpus work
c54a1b09-7dfa-5bda-af0f-b7ef99fa8c0d
DOI
10.21203/rs.3.rs-5743295/v1
Open publication

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Targeting Oncofetal Fibronectin and Neuropilin-1 in solid tumors with PL2 peptideDOI 10.21203/rs.3.rs-5743295/v1
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