Article

Myelin lipids as nervous system energy reserves

2022-02-25

Abstract excerpt

Neuronal functions and impulse propagation depend on the continuous supply of glucose 1,2 . Surprisingly, the mammalian brain has no obvious energy stores, except for astroglial glycogen granules 3 . Oligodendrocytes make myelin for rapid axonal impulse conduction 4 and also support axons metabolically with lactate 5–7 . Here, we show that myelin itself, a lipid-rich membrane compartment, becomes a local energ...

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Literature Corpus work: 9403c8aa-0362-5c08-b6f6-297270ab385f
DOI: 10.1101/2022.02.24.481621

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