Article

Mapping Decidualization Resistance in Former Severe Preeclampsia Patients at Multi-Omic Levels

2024-05-06

Abstract excerpt

<title>Abstract</title> <p>Endometrial decidualization resistance (DR) is implicated in various gynaecological and obstetric conditions. Employing a multi-omic strategy, we unraveled the cellular and molecular characteristics of DR in patients that have suffered severe preeclampsia (sPE). Morphological analysis unveiled significant glandular anatomical abnormalities, confirmed histologically. Single-cell RNA sequ...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 93eb6f86-f850-560a-b9b4-9ee797aa6c08
DOI: 10.21203/rs.3.rs-4331532/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Mapping Decidualization Resistance in Former Severe Preeclampsia Patients at Multi-Omic LevelsDOI 10.21203/rs.3.rs-4331532/v1Read

Multi-omics-based mapping of decidualization resistance in patients with a history of severe preeclampsiaSemantic proximity Read

Decoding the endometrial niche of Asherman’s Syndrome at single-cell resolutionSemantic proximity Read

Decoding the endometrial niche of Asherman’s Syndrome at single-cell resolutionSemantic proximity Read

Cellular heterogeneity and dynamics of the human uterus in healthy premenopausal womenSemantic proximity Read

Single-cell transcriptional profiling reveals cellular and molecular divergence in human maternal–fetal interfaceSemantic proximity Read

Cellular heterogeneity and dynamics of the human uterus in healthy premenopausal womenSemantic proximity Read

Single-cell RNA-seq reveals developmental deficiencies in both the placentation and the decidualization in women with late-onset preeclampsiaSemantic proximity Read

HSD17B1-mediated trophoblast differentiation lowers estrogen levels in early-onset preeclampsiaSemantic proximity Read

Transcriptomic comparison of early onset preeclampsia and placenta accreta identifies inverse trophoblast and decidua functions at the maternal-fetal interfaceSemantic proximity Read

Single‐cell transcriptome analysis reveals defective decidua stromal niche attributes to recurrent spontaneous abortionSemantic proximity Read

The maternal-fetal interface of successful pregnancies and impact of fetal sex using single cell sequencingSemantic proximity Read

Single-cell mapping of maternal–fetal cross-talk in preeclampsiaSemantic proximity Read