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Multi-omics-based mapping of decidualization resistance in patients with a history of severe preeclampsia

7 Jan 2025

Abstract excerpt

Endometrial decidualization resistance (DR) is implicated in various gynecological and obstetric conditions. Here, using a multi-omic strategy, we unraveled the cellular and molecular characteristics of DR in patients who have suffered severe preeclampsia (sPE). Morphological analysis unveiled significant glandular anatomical abnormalities, confirmed histologically and quantified by the digitization of...

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PMID: 39775038
DOI: 10.1038/s41591-024-03407-7

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