Article
Single‐cell transcriptome analysis reveals defective decidua stromal niche attributes to recurrent spontaneous abortion
21 Sept 2021
Abstract excerpt
OBJECTIVES: Successful pregnancy involves the homeostasis between maternal decidua and fetoplacental units, whose disruption contributes to compromised pregnancy outcomes, including recurrent spontaneous abortion (RSA). The role of cell heterogeneity of maternal decidua in RSA is yet to be illustrated. MATERIALS AND METHODS: A total of 66,078 single cells from decidua samples isolated from patients with RSA and...
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