Article

Expressing multiple genes in a single open reading frame with the 2A region of foot-and-mouth disease virus as a linker

2002-01-01

Abstract excerpt

The Food-and-mouth disease virus (FMDV) 2A protein is only 16-20 amino acids long. It is responsible for the 'cleavage' of the FMDV polyprotein at its own carboxyl-terminus. We used the 'cleavage' property of the 2A protein to process artificial polyproteins produced in transgenic plants. In our system, single or multiple copies of the reporter CAT and GUS genes were fused into a single open reading frame (ORF) wi...

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Literature Corpus work: 93ca7e98-ea0c-5f9a-80fe-b246d4bd37f9
DOI: 10.1023/a:1019760127368

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