Article

A Multi-Cohort Study of Immunoglobulin G Glycans in Newly Diagnosed Inflammatory Bowel Disease Patients Reveals Accelerated Biological Aging

2026-04-11

Abstract excerpt

<h4>Background and Aims</h4> Alterations in immunoglobulin G (IgG) N-glycosylation are implicated in inflammatory bowel disease (IBD); however, the robustness of IgG glycan signatures across IBD cohorts with diverse demographics and geographic origins remains underexplored. We aimed to determine whether compositional data analysis (CoDA) and machine learning (ML) can identify IBD-related IgG N-glycan signatures a...

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Literature Corpus work: 93bc5447-27cf-5dce-bcea-a2e9e2bb79ff
DOI: 10.64898/2026.04.10.26349930

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