Article

Inhibition of melanogenesis by the extract from Agaricus blazei without affecting iNOS gene expression

2010-11-01

Abstract excerpt

Tyrosinase is a key enzyme in melanin synthesis. Owing to enlargement of availability of edible types of mushrooms in food medicines, we investigated effects of Agaricus blazei (ABE) on tyrosinase activity using l-tyrosine and l-3, 4-dihydroxyphenylalanine (l-DOPA) as the substrate in normal human epidermal melanocytes (NHEM). ABE inhibited tyrosinase activity similar to arbutin and Vitamin C as two whitening agen...

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Literature Corpus work: 937adddc-00c5-5a9c-86bc-5007db7a831d
DOI: 10.1007/s11274-010-0387-6

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