Article

PI3K/AKT/GSK-3β signaling pathway involving in the mechanism of polymyxin B induced melanogenesis

2022-03-30

Abstract excerpt

<h4>Backgrounds: </h4>: Polymyxin B， which is a last line antibiotic for multi-drug resistant gram-negative bacteria, has been reported to induce skin hyperpigmentation in patients during treatments. 8~15% or more cases were reported hyperpigmentation, especially in head and neck, seriously influencing the compliance of patients. To investigate the mechanism of hyperpigmentation is beneficial for intervention stra...

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Literature Corpus work: aacb8270-d211-53e0-a3c7-3b230978e402
DOI: 10.22541/au.164864255.52225423/v1

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