Article

Systematic comparison of Mendelian randomization studies and randomized controlled trials using electronic databases

2022-04-16

Abstract excerpt

Mendelian Randomization (MR) uses genetic instrumental variables to make causal inferences. Whilst sometimes referred to as “nature’s randomized trial”, it has distinct assumptions that make comparisons between the results of MR studies with those of actual randomized controlled trials (RCTs) invaluable. To scope the potential for (semi-)-automated triangulation of MR and RCT evidence, we mined ClinicalTrials.Gov...

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Literature Corpus work: 2285dae6-9244-5be8-9f1d-4686e2c5dfdd
DOI: 10.1101/2022.04.11.22273633

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