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Article

Increasing the sensitivity, recovery, and integrality of spatially resolved proteomics by LCM-MTA

2022-08-22

Abstract excerpt

Conventional proteomic approaches neglect tissue heterogeneity and spatial localization information. Laser capture microdissection (LCM) can isolate specific cell populations or histological areas from heterogeneous tissue specimens while preserving spatial localization information. Formalin-fixed paraffin-embedded (FFPE) is currently a standardized method for long-term stable preservation of clinical tissue speci...

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Literature Corpus work
9325f112-7479-52aa-9441-e8f71ef62a99
DOI
10.1101/2022.08.21.504675
Open publication

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