Article

An automated and fast sample preparation workflow for laser microdissection guided ultrasensitive proteomics

2023-12-01

Abstract excerpt

<h4>ABSTRACT</h4> Spatial tissue proteomics integrating whole-slide imaging, laser microdissection and ultrasensitive mass spectrometry is a powerful approach to link cellular phenotypes to functional proteome states in (patho)physiology. To be applicable to large patient cohorts and low sample input amounts, including single-cell applications, loss-minimized and streamlined end-to-end workflows are key. We here...

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Literature Corpus work: 217f19c0-6c6b-5310-9fd1-fcb2487a61dd
DOI: 10.1101/2023.11.29.569257

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