Article

Ectopic <i>hAMH</i> -driven SOX17 expression induces hyperplastic Sertoli valve formation in mouse testes

2026-05-12

Abstract excerpt

In the terminal segment of the seminiferous tubules, SOX17 expression in the rete testis (RT) epithelium plays a crucial role in the formation of the Sertoli valve (SV), as revealed by phenotypic analyses of RT-specific Sox17 conditional knockout (cKO) mouse testes. In these RT-specific Sox17 cKO testes, SV disruption leads to the backflow of RT fluid into the seminiferous tubules, resulting in defective spermio...

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Literature Corpus work: 92fa84bb-cd0f-5c7b-97fc-24c0273f430f
DOI: 10.64898/2026.05.08.723552

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