Article
Sox7 and Sox17 are strain-specific modifiers of the lymphangiogenic defects caused by Sox18 dysfunction in mice.
Development (Cambridge, England) - 1 Jul 2009
Hosking Brett, François Mathias, Wilhelm Dagmar, Orsenigo Fabrizio, Caprini Andrea, Svingen Terje, Tutt Desmond, Davidson Tara, Browne Catherine, Dejana Elisabetta, Koopman Peter
Abstract excerpt
Developmental defects caused by targeted gene inactivation in mice are commonly subject to strain-specific modifiers that modulate the severity of the phenotype. Although several genetic modifier loci have been mapped in mice, the gene(s) residing at these loci are mostly unidentified, and the mo...
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