Article

Oral Vitamin D supplementation induces transcriptomic changes in rectal mucosa that are consistent with anti-tumour effects

2021-05-10

Abstract excerpt

<h4>Background</h4> Risk for several common cancers is influenced by the transcriptomic landscape of the respective tissue-of-origin. Vitamin D influences in-vitro gene expression and cancer cell growth. We sought to determine whether oral vitamin D induces beneficial gene expression effects in human rectal epithelium and identify biomarkers of response. <h4>Methods</h4> Blood and rectal mucosa was sampled from 19...

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Literature Corpus work: 3718d68c-3300-5adf-9a7c-d9012756d184
DOI: 10.1101/2021.05.04.21255629

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